专利名称：NANOPARTICLE DRUG DELIVERY SYSTEM
AND METHOD OF TREATING CANCER ANDNEUROTRAUMA
发明人：Shifalika TANGUTOORI,Srinivas SRIDHAR申请号：US14914932申请日：20140827
公开号：US20160206615A1公开日：20160721
摘要：The invention provides pharmaceutical formulations of inhibitors for poly (ADP-ribose) polymerase (PARP) enzyme. The formulations can be used in the treatment andprevention of cancer as well as the treatment of neurotrauma and neurodegenerativediseases. The PARP inhibitor is delivered in the form of nanoparticles that provideefficient delivery of the inhibitor into cancer cells or other cells and release of theinhibitor within the cells. In treating cancer, the result is killing of tumor cells, whereas intreatment of neurotrauma and neurodegenerative disease, the result is preservation ofcell function.
申请人：Northeastern University
地址：Boston MA US
国籍：US
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